IRGM is a common target of RNA viruses that subvert the autophagy network.

Autophagy is a conserved degradative pathway used as a host defense mechanism against intracellular pathogens. However, several viruses can evade or subvert autophagy to insure their own replication. Nevertheless, the molecular details of viral interaction with autophagy remain largely unknown. We h...

Full description

Bibliographic Details
Main Authors: Isabel Pombo Grégoire, Clémence Richetta, Laurène Meyniel-Schicklin, Sophie Borel, Fabrine Pradezynski, Olivier Diaz, Alexandre Deloire, Olga Azocar, Joël Baguet, Marc Le Breton, Philippe E Mangeot, Vincent Navratil, Pierre-Emmanuel Joubert, Monique Flacher, Pierre-Olivier Vidalain, Patrice André, Vincent Lotteau, Martine Biard-Piechaczyk, Chantal Rabourdin-Combe, Mathias Faure
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22174682/?tool=EBI