TRIM72 promotes alveolar epithelial cell membrane repair and ameliorates lung fibrosis

TRIM72 promotes alveolar epithelial cell membrane repair and ameliorates lung fibrosis

Abstract Background Chronic tissue injury was shown to induce progressive scarring in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF), while an array of repair/regeneration and stress responses come to equilibrium to determine the outcome of injury at the organ level. In the lung, type...

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Bibliographic Details
Main Authors: Xiaofei Cong, Nagaraja Nagre, Jeremy Herrera, Andrew C. Pearson, Ian Pepper, Robell Morehouse, Hong-Long Ji, Dianhua Jiang, Rolf D. Hubmayr, Xiaoli Zhao
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Respiratory Research
Subjects:
Idiopathic pulmonary fibrosis
Tripartite motif family protein 72
Alveolar epithelial cells
Membrane repair
Apoptosis
Online Access:http://link.springer.com/article/10.1186/s12931-020-01384-2

Internet

http://link.springer.com/article/10.1186/s12931-020-01384-2

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