The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by charged gatekeeper residues alone

The nucleotide specificity of succinyl‐CoA synthetase of Plasmodium falciparum is not determined by charged gatekeeper residues alone

Substrate specificity of an enzyme is an important characteristic of its mechanism of action. Investigation of the nucleotide specificity of Plasmodium falciparum succinyl‐CoA synthetase (SCS; PfSCS) would provide crucial insights of its substrate recognition. Charged gatekeeper residues have been s...

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Bibliographic Details
Main Authors: Kapil Vashisht, Pallavi Singh, Sonia Verma, Rajnikant Dixit, Neelima Mishra, Kailash C. Pandey
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:FEBS Open Bio
Subjects:
gatekeeper residues
malaria
Plasmodium falciparum
site‐directed mutagenesis
substrate specificity
succinyl‐CoA synthetase
Online Access:https://doi.org/10.1002/2211-5463.13034

Internet

https://doi.org/10.1002/2211-5463.13034

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