Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism

Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism

In this overview, we provide an update on recent progress made in understanding the mechanisms of action, physiological functions, and roles in disease of retinoic acid related orphan receptors (RORs). We are particularly focusing on their roles in the regulation of adaptive and innate immunity, bra...

Full description

Bibliographic Details
Main Authors: Donald N. Cook, Hong Soon Kang, Anton M. Jetten
Format: Article
Language:English
Published: KenzPub 2015-12-01
Series:Nuclear Receptor Research
Subjects:
retinoic acid-related orphan receptor
RORγ
RORα
RORβ
immunity
Th17 cells
innate lymphoid cells
autoimmune disease
retina
brain
cancer
metabolism
glucose homeostasis
lipid metabolism
insulin sensitivity
diabetes
circadian clock
agonists
cholesterol biosynthesis
autism
antagonist
transcription
Online Access:http://www.kenzpub.com/journals/nurr/2015/101185/

Internet

http://www.kenzpub.com/journals/nurr/2015/101185/

Similar Items