Phosphoinositide 3-kinase p85beta regulates invadopodium formation

Phosphoinositide 3-kinase p85beta regulates invadopodium formation

The acquisition of invasiveness is characteristic of tumor progression. Numerous genetic changes are associated with metastasis, but the mechanism by which a cell becomes invasive remains unclear. Expression of p85β, a regulatory subunit of phosphoinositide-3-kinase, markedly increases in advanced c...

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Bibliographic Details
Main Authors: Ariel E. Cariaga-Martínez, Isabel Cortés, Esther García, Vicente Pérez-García, María J. Pajares, Miguel A. Idoate, Javier Redondo-Muñóz, Inés M. Antón, Ana C. Carrera
Format: Article
Language:English
Published: The Company of Biologists 2014-09-01
Series:Biology Open
Subjects:
p85β
invadopodium
invasion
cell adhesion
metastasis
Online Access:http://bio.biologists.org/content/3/10/924

Internet

http://bio.biologists.org/content/3/10/924

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