LncRNA NEAT1 in Paraspeckles: A Structural Scaffold for Cellular DNA Damage Response Systems?

LncRNA NEAT1 in Paraspeckles: A Structural Scaffold for Cellular DNA Damage Response Systems?

Nuclear paraspeckle assembly transcript 1 (NEAT1) is a long non-coding RNA (lncRNA) reported to be frequently deregulated in various types of cancers and neurodegenerative processes. NEAT1 is an indispensable structural component of paraspeckles (PSs), which are dynamic and membraneless nuclear bodi...

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Bibliographic Details
Main Authors: Elisa Taiana, Domenica Ronchetti, Katia Todoerti, Lucia Nobili, Pierfrancesco Tassone, Nicola Amodio, Antonino Neri
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Non-Coding RNA
Subjects:
lncRNA
NEAT1
paraspeckle
DNA damage repair
cancer
neurodegenerative disease
Online Access:https://www.mdpi.com/2311-553X/6/3/26

Internet

https://www.mdpi.com/2311-553X/6/3/26

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