Identification of Direct Activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by Structure-Based Virtual Screening and Molecular Docking Approach

Identification of Direct Activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by Structure-Based Virtual Screening and Molecular Docking Approach

Adenosine monophosphate-activated protein kinase (AMPK) plays a critical role in the regulation of energy metabolism and has been targeted for drug development of therapeutic intervention in Type II diabetes and related diseases. Recently, there has been renewed interest in the development of direct...

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Bibliographic Details
Main Authors: Tonghui Huang, Jie Sun, Shanshan Zhou, Jian Gao, Yi Liu
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:International Journal of Molecular Sciences
Subjects:
Adenosine 5′-monophosphate-activated protein kinase
virtual screening
molecular docking
selective activator
Online Access:http://www.mdpi.com/1422-0067/18/7/1408

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http://www.mdpi.com/1422-0067/18/7/1408

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