The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.

The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons.

Swiprosin-1/EFhd2 (EFhd2) is a cytoskeletal Ca2+ sensor protein strongly expressed in the brain. It has been shown to interact with mutant tau, which can promote neurodegeneration, but nothing is known about the physiological function of EFhd2 in the nervous system. To elucidate this question, we an...

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Bibliographic Details
Main Authors: Pavitra Purohit, Francesc Perez-Branguli, Iryna Prots, Eva Borger, Frank Gunn-Moore, Oliver Welzel, Kristina Loy, Eva Maria Wenzel, Teja W Grömer, Sebastian Brachs, Max Holzer, Rolf Buslei, Kristin Fritsch, Martin Regensburger, Konrad J Böhm, Beate Winner, Dirk Mielenz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4136728?pdf=render

Internet

http://europepmc.org/articles/PMC4136728?pdf=render

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