Isolation and Biochemical Characterization of a New Thrombin-Like Serine Protease from Bothrops pirajai Snake Venom

This paper presents a novel serine protease (SP) isolated from Bothrops pirajai, a venomous snake found solely in Brazil that belongs to the Viperidae family. The identified SP, named BpirSP-39, was isolated by three chromatographic steps (size exclusion, bioaffinity, and reverse phase chromatograp...

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Main Authors: Kayena D. Zaqueo, Anderson M. Kayano, Rodrigo Simões-Silva, Leandro S. Moreira-Dill, Carla F. C. Fernandes, André L. Fuly, Vinícius G. Maltarollo, Kathia M. Honório, Saulo L. da Silva, Gerardo Acosta, Maria Antonia O. Caballol, Eliandre de Oliveira, Fernando Albericio, Leonardo A. Calderon, Andreimar M. Soares, Rodrigo G. Stábeli
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/595186