Alternative statistical methods for estimating efficacy of interferon beta-1b for multiple sclerosis clinical trials

<p>Abstract</p> <p>Background</p> <p>In the randomized study of interferon beta-1b (IFN beta-1b) for multiple sclerosis (MS), it has usually been evaluated the simple annual relapse rate as the study endpoint. This study aimed to investigate the performance of various r...

Full description

Bibliographic Details
Main Authors: Yamaguchi Takuhiro, Mieno Makiko N, Ohashi Yasuo
Format: Article
Language:English
Published: BMC 2011-05-01
Series:BMC Medical Research Methodology
Online Access:http://www.biomedcentral.com/1471-2288/11/80