Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

<p>Abstract</p> <p>Background</p> <p>Prior studies have demonstrated that the distal 1.5 kb of the MMP-1 promoter is fundamental in directing the induction of the MMP-1 gene by cigarette smoke.</p> <p>Methods</p> <p>To characterize the genetic va...

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Bibliographic Details
Main Authors: Wallace Alison M, Mercer Becky A, He Jianqing, Foronjy Robert F, Accili Domenico, Sandford Andrew J, Paré Peter D, D’Armiento Jeanine M
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Respiratory Research
Subjects:
Chromatin immunoprecipitation
COPD
Metalloproteinase
Polymorphisms
Transcription factors
Online Access:http://respiratory-research.com/content/13/1/79

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http://respiratory-research.com/content/13/1/79

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