DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

DNMT (DNA methyltransferase) inhibitors radiosensitize human cancer cells by suppressing DNA repair activity

<p>Abstract</p> <p>Background</p> <p>Histone modifications and DNA methylation are two major factors in epigenetic phenomenon. Unlike the histone deacetylase inhibitors, which are known to exert radiosensitizing effects, there have only been a few studies thus far conce...

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Bibliographic Details
Main Authors: Kim Hak Jae, Kim Jin Ho, Chie Eui Kyu, Da Young Park, Kim In Ah, Kim Il Han
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Radiation Oncology
Subjects:
Cancer
Epigenetics
DNA methylation
DNA methyltransferase inhibitor
Radiosensitization
Online Access:http://www.ro-journal.com/content/7/1/39

Internet

http://www.ro-journal.com/content/7/1/39

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