Chronic and intermittent administration of systemic nitroglycerin in the rat induces an increase in the gene expression of CGRP in central areas: potential contribution to pain processing
Abstract Background Calcitonin gene related peptide (CGRP) is a key neuropeptide involved in the activation of the trigeminovascular system and it is likely related to migraine chronification. Here, we investigated the role of CGRP in an animal model that mimics the chronic migraine condition via re...
Main Authors: | Rosaria Greco, Chiara Demartini, Anna Maria Zanaboni, Cristina Tassorelli |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | The Journal of Headache and Pain |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s10194-018-0879-6 |
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