The association between CD8+ tumor-infiltrating lymphocytes and the clinical outcome of cancer immunotherapy: A systematic review and meta-analysis

Background: The responses of cancer patients to immune checkpoint inhibitors (ICIs) vary in success. CD8+ tumor infiltrating lymphocytes (TILs) play a key role in killing tumor cells. This study aims to evaluate the prognostic role of CD8+ TILs in cancer patients treated with ICIs. Methods: We syste...

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Bibliographic Details
Main Authors: Feng Li, Caichen Li, Xiuyu Cai, Zhanhong Xie, Liquan Zhou, Bo Cheng, Ran Zhong, Shan Xiong, Jianfu Li, Zhuxing Chen, Ziwen Yu, Jianxing He, Wenhua Liang
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:EClinicalMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537021004144