Dissecting G<sub>q/11</sub>-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1

Dissecting G<sub>q/11</sub>-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1

Diverse extracellular signals induce plasma membrane translocation of sphingosine kinase-1 (SphK1), thereby enabling inside-out signaling of sphingosine-1-phosphate. We have shown before that G<sub>q</sub>-coupled receptors and constitutively active Gα<sub>q/11</sub> specific...

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Bibliographic Details
Main Authors: Kira Vanessa Blankenbach, Ralf Frederik Claas, Natalie Judith Aster, Anna Katharina Spohner, Sandra Trautmann, Nerea Ferreirós, Justin L. Black, John J. G. Tesmer, Stefan Offermanns, Thomas Wieland, Dagmar Meyer zu Heringdorf
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
sphingosine kinase
sphingosine-1-phosphate
G-protein-coupled receptors
Gα<sub>q/11</sub>
Online Access:https://www.mdpi.com/2073-4409/9/10/2201

Internet

https://www.mdpi.com/2073-4409/9/10/2201

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