A selective cyclic integrin antagonist blocks the integrin receptors α<sub>v</sub>β<sub>3 </sub>and α<sub>v</sub>β<sub>5 </sub>and inhibits retinal pigment epithelium cell attachment, migration and invasion

A selective cyclic integrin antagonist blocks the integrin receptors α<sub>v</sub>β<sub>3 </sub>and α<sub>v</sub>β<sub>5 </sub>and inhibits retinal pigment epithelium cell attachment, migration and invasion

<p>Abstract</p> <p>Background</p> <p>Proliferative vitreoretinopathy (PVR) is a leading cause of blindness after failed retinal reattachment surgery. PVR is characterized by the proliferation, migration and contraction of retinal pigmented epithelial cells (RPE), and th...

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Bibliographic Details
Main Authors: Wiedemann Peter, Ehren Marianne, Jin Manlin, He Shikun, Hoffmann Stephan, Ryan Stephen J, Hinton David R
Format: Article
Language:English
Published: BMC 2005-06-01
Series:BMC Ophthalmology
Online Access:http://www.biomedcentral.com/1471-2415/5/16

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http://www.biomedcentral.com/1471-2415/5/16

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