Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

Elucidating the Kinetics of Expression and Immune Cell Infiltration Resulting from Plasmid Gene Delivery Enhanced by Surface Dermal Electroporation

The skin is an attractive tissue for vaccination in a clinical setting due to the accessibility of the target, the ease of monitoring and most importantly the immune competent nature of the dermal tissue. While skin electroporation offers an exciting and novel future methodology for the delivery of...

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Bibliographic Details
Main Authors: Kate E. Broderick, Niranjan Y. Sardesai, Trevor R. F. Smith, William B. Kiosses, Christine L. Knott, Gleb Kichaev, Dinah H. Amante, Janess M. Mendoza
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Vaccines
Subjects:
intradermal
DNA vaccine
electroporation
kinetics
infiltration
Online Access:http://www.mdpi.com/2076-393X/1/3/384

Internet

http://www.mdpi.com/2076-393X/1/3/384

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