The Environment of Regulatory T Cell Biology: Cytokines, Metabolites and the Microbiome

Regulatory T cells (Tregs) are suppressive T cells that have an essential role in maintaining the balance between immune activation and tolerance. Their development, either in the thymus, periphery, or experimentally in vitro, and stability and function all depend on the right mix of environmental s...

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Bibliographic Details
Main Authors: Romy Eleonora Hoeppli, Dan eWu, Laura eCook, Megan K Levings
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00061/full