Chronic Fluoxetine Induces the Enlargement of Perforant Path-Granule Cell Synapses in the Mouse Dentate Gyrus.

A selective serotonin reuptake inhibitor is the most commonly prescribed antidepressant for the treatment of major depression. However, the mechanisms underlying the actions of selective serotonin reuptake inhibitors are not fully understood. In the dentate gyrus, chronic fluoxetine treatment induce...

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Bibliographic Details
Main Authors: Yosuke Kitahara, Keisuke Ohta, Hiroshi Hasuo, Takahide Shuto, Mahomi Kuroiwa, Naoki Sotogaku, Akinobu Togo, Kei-ichiro Nakamura, Akinori Nishi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4720354?pdf=render