Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice.

Intermedin stabilized endothelial barrier function and attenuated ventilator-induced lung injury in mice.

Even protective ventilation may aggravate or induce lung failure, particularly in preinjured lungs. Thus, new adjuvant pharmacologic strategies are needed to minimize ventilator-induced lung injury (VILI). Intermedin/Adrenomedullin-2 (IMD) stabilized pulmonary endothelial barrier function in vitro....

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Bibliographic Details
Main Authors: Holger Christian Müller-Redetzky, Wolfgang Kummer, Uwe Pfeil, Katharina Hellwig, Daniel Will, Renate Paddenberg, Christoph Tabeling, Stefan Hippenstiel, Norbert Suttorp, Martin Witzenrath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3341380?pdf=render

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http://europepmc.org/articles/PMC3341380?pdf=render

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