The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions

The Importance of Caveolin-1 as Key-Regulator of Three-Dimensional Growth in Thyroid Cancer Cells Cultured under Real and Simulated Microgravity Conditions

We recently demonstrated that the CAV1 gene was down-regulated, when poorly differentiated thyroid FTC-133 cancer cells formed spheroids under simulated microgravity conditions. Here, we present evidence that the caveolin-1 protein is involved in the inhibition of spheroid formation, when confluent...

Full description

Bibliographic Details
Main Authors: Stefan Riwaldt, Johann Bauer, Jessica Pietsch, Markus Braun, Jürgen Segerer, Achim Schwarzwälder, Thomas J. Corydon, Manfred Infanger, Daniela Grimm
Format: Article
Language:English
Published: MDPI AG 2015-11-01
Series:International Journal of Molecular Sciences
Subjects:
international space station
pathway studio
plasminogen
tissue factor
VCAM-1
Online Access:http://www.mdpi.com/1422-0067/16/12/26108

Internet

http://www.mdpi.com/1422-0067/16/12/26108

Similar Items