Efficient Synthesis of a (Z)-3-Methyleneisoindolin-1-one Library Using Cu(OAc)2•H2O/DBU under Microwave Irradiation

Microwave-promoted efficient synthesis of a (Z)-3-methyleneisoindolin-1-one library from 2-bromobenzamides and terminal alkynes using Cu(OAc)2•H2O/DBU is described. Various benzamide substituents, ring substitutions, including heteroaryl, aryl acetylenes and aliphatic alkynes, could be...

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Bibliographic Details
Main Authors: Li Zhang, Yongliang Zhang, Xin Wang, Jingkang Shen
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/1/654