Anti-Insulin Immune Responses Are Detectable in Dogs with Spontaneous Diabetes.

Diabetes mellitus occurs spontaneously in dogs. Although canine diabetes shares many features with human type-1 diabetes, there are differences that have cast doubt on the immunologic origin of the canine disease. In this study, we examined whether peripheral immune responses directed against islet...

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Bibliographic Details
Main Authors: Jong-Hyuk Kim, Eva Furrow, Michelle G Ritt, Paul J Utz, William H Robinson, Liping Yu, Andrea Eckert, Kathleen Stuebner, Timothy D O'Brien, Lawrence Steinman, Jaime F Modiano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4816536?pdf=render