Impact of capsular switch on invasive pneumococcal disease incidence in a vaccinated population.

BACKGROUND: Despite the dramatic decline in the incidence of invasive pneumococcal disease (IPD) observed since the introduction of conjugate vaccination, it is feared that several factors may undermine the future effectiveness of the vaccines. In particular, pathogenic pneumococci may switch their...

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Bibliographic Details
Main Authors: Laura Temime, Pierre-Yves Boelle, Lulla Opatowski, Didier Guillemot
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2531230?pdf=render