Forebrain NgR1 Overexpression Impairs DA Release Suggesting Synergy of Local and Global Synaptic Plasticity Mechanisms

Forebrain NgR1 Overexpression Impairs DA Release Suggesting Synergy of Local and Global Synaptic Plasticity Mechanisms

Structural synaptic reorganizations needed to permanently embed novel memories in the brain involve complex plasticity-enhancing and plasticity-inhibiting systems. Increased neural activity is linked to rapid downregulation of Nogo receptor 1 (NgR1), needed to allow local structural synaptic plastic...

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Bibliographic Details
Main Authors: Emma Arvidsson, Sarolta Gabulya, Alvin Tore Brodin, Tobias Erik Karlsson, Lars Olson
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Nogo receptor 1
Nogo
plasticity
substantia nigra
striatum
MemoFlex mouse
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2020.545854/full

Internet

https://www.frontiersin.org/articles/10.3389/fnsyn.2020.545854/full

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