EGF Receptor Stalls upon Activation as Evidenced by Complementary Fluorescence Correlation Spectroscopy and Fluorescence Recovery after Photobleaching Measurements

To elucidate the molecular details of the activation-associated clustering of epidermal growth factor receptors (EGFRs), the time course of the mobility and aggregation states of eGFP tagged EGFR in the membranes of Chinese hamster ovary (CHO) cells was assessed by in situ mobility assays. Fluoresce...

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Bibliographic Details
Main Authors: György Vámosi, Elza Friedländer-Brock, Shehu M. Ibrahim, Roland Brock, János Szöllősi, György Vereb
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
FCS
Online Access:https://www.mdpi.com/1422-0067/20/13/3370