Inactivation of rat liver HMG-CoA reductase phosphatases by polycarboxylic acids.
Incubation of the four purified HMG-CoA reductase phosphatases with the sodium salts of eleven polycarboxylic acids at concentrations of 40 mM, inactivated the enzymes to different degrees depending on the structure of the carboxylic acids. Maleate, malonate, oxalate, citrate, and hydroxymethylgluta...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
1983-07-01
|
Series: | Journal of Lipid Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S002222752037927X |