Neuroprotection by curcumin in ischemic brain injury involves the Akt/Nrf2 pathway.

Oxidative damage plays a critical role in many diseases of the central nervous system. This study was conducted to determine the molecular mechanisms involved in the putative anti-oxidative effects of curcumin against experimental stroke. Oxygen and glucose deprivation/reoxygenation (OGD/R) was used...

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Bibliographic Details
Main Authors: Jingxian Wu, Qiong Li, Xiaoyan Wang, Shanshan Yu, Lan Li, Xuemei Wu, Yanlin Chen, Jing Zhao, Yong Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3610879?pdf=render