Calcium Oxalate Differentiates Human Monocytes Into Inflammatory M1 Macrophages

PurposeA number of hyperoxaluric states have been associated with calcium oxalate (CaOx) deposits in the kidneys. In animal models of stone disease, these crystals interact with circulating monocytes that have migrated into the kidney as part of innate immunity. Similarly, macrophages surround CaOx...

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Bibliographic Details
Main Authors: Paul R. Dominguez-Gutierrez, Sergei Kusmartsev, Benjamin K. Canales, Saeed R. Khan
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01863/full