Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines.

Metastasis accounts for more than 90% of cancer deaths. Cells from primary solid tumors may invade adjacent tissues and migrate to distant sites where they establish new colonies. The tumor microenvironment is now recognized as an important participant in the signaling that induces cancer cell migra...

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Main Authors: Isabela T Pereira, Edneia A S Ramos, Erico T Costa, Anamaria A Camargo, Graciele C M Manica, Liliane M B Klassen, Andressa Chequin, Karin Braun-Prado, Fábio de O Pedrosa, Emanuel M Souza, Fabricio F Costa, Giseli Klassen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4160184?pdf=render