Constitutive and LPS-stimulated secretome of porcine Vascular Wall-Mesenchymal Stem Cells exerts effects on in vitro endothelial angiogenesis

Abstract Background MSCs secretome is under investigation as an alternative to whole-cell-based therapies, since it is enriched of bioactive molecules: growth factors, cytokines and chemokines. Taking into account the translational value of the pig model, the leading aim of the present paper was to...

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Bibliographic Details
Main Authors: Chiara Bernardini, Martina Bertocchi, Augusta Zannoni, Roberta Salaroli, Irvin Tubon, Giovanni Dothel, Mercedes Fernandez, Maria Laura Bacci, Laura Calzà, Monica Forni
Format: Article
Language:English
Published: BMC 2019-04-01
Series:BMC Veterinary Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12917-019-1873-1