GATA6 Promotes Colon Cancer Cell Invasion by Regulating Urokinase Plasminogen Activator Gene Expression

GATA6 is a zinc finger transcription factor expressed in the colorectal epithelium. We have examined the expression of GATA6 in colon cancers and investigated the mechanisms by which GATA6 regulates colon cancer cell invasion. GATA6 was overexpressed in colorectal polyps and primary and metastatic...

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Bibliographic Details
Main Authors: Narasimhaswamy S Belaguli, Muhammad Aftab, Mohammed Rigi, Mao Zhang, Daniel Albo, David H Berger
Format: Article
Language:English
Published: Elsevier 2010-11-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861080034X