Inhibition of Acetylcholinesterase in Different Structures of the Rat Brain Following Soman Intoxication Pretreated with Huperzine A

Inhibition of Acetylcholinesterase in Different Structures of the Rat Brain Following Soman Intoxication Pretreated with Huperzine A

Acetylcholinesterase (AChE) activities in different brain parts were determinedquantitatively in rats treated with huperzine A, soman, and huperzine A followed bysoman, using histochemical and biochemical methods. Following soman intoxication (1.2x LD50, i.m.), AChE activity was decreased to 30-80%...

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Bibliographic Details
Main Authors: Lukas Capek, Josef Fusek, Daniel Jun, Kamil Kuca, Otakar Krs, Dasa Slizova, Jana Karasova, Petr Hajek, Jiri Bajgar
Format: Article
Language:English
Published: MDPI AG 2007-11-01
Series:International Journal of Molecular Sciences
Subjects:
acetylcholinesterase
rat brain parts
soman
Huperzine A
pretreatment
Online Access:http://www.mdpi.com/1422-0067/8/11/1165/

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http://www.mdpi.com/1422-0067/8/11/1165/

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