Identification of free nitric oxide radicals in rat bone marrow: implications for progenitor cell mobilization in hypertension.

Nitric oxide (NO) has been implicated in matrix metallopeptidase 9 (MMP9)-dependent mobilization of hematopoietic stem and progenitor cells from bone marrow (BM). However, direct measurement of NO in the BM remained elusive due to its low in situ concentration and short lifetime. Using NO spin trapp...

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Bibliographic Details
Main Authors: Marina A Aleksinskaya, Ernst E H van Faassen, Jelly Nelissen, Ben J A Janssen, Jo G R De Mey, Roeland Hanemaaijer, Ton Rabelink, Anton Jan van Zonneveld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3595254?pdf=render