miR-223 Inhibits Lipid Deposition and Inflammation by Suppressing Toll-Like Receptor 4 Signaling in Macrophages

miR-223 Inhibits Lipid Deposition and Inflammation by Suppressing Toll-Like Receptor 4 Signaling in Macrophages

Atherosclerosis and its complications rank as the leading cause of death with the hallmarks of lipid deposition and inflammatory response. MicroRNAs (miRNAs) have recently garnered increasing interests in cardiovascular disease. In this study, we investigated the function of miR-223 and the underl...

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Bibliographic Details
Main Authors: Jun Wang, Xiaojun Bai, Qiang Song, Fenling Fan, Zhi Hu, Gesheng Cheng, Yushun Zhang
Format: Article
Language:English
Published: MDPI AG 2015-10-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
inflammatory
lipid accumulation
miR-223
PI3K/AKT
TLR4
Online Access:http://www.mdpi.com/1422-0067/16/10/24965

Internet

http://www.mdpi.com/1422-0067/16/10/24965

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