Dusp1 modulates activin/smad2 mediated germ layer specification via FGF signal inhibition in Xenopus embryos

Activin, a member of the transforming growth factor (TGF-β) superfamily, induces mesoderm, endoderm and neuro-ectoderm formation in Xenopus embryos. Despite several previous studies, the complicated gene regulatory network and genes involved in this induction await more elaboration. We identified ex...

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Bibliographic Details
Main Authors: Zobia Umair, Santosh Kumar, Khezina Rafiq, Vijay Kumar, Zia Ur Reman, Seung-Hwan Lee, SungChan Kim, Jae-Yong Lee, Unjoo Lee, Jaebong Kim
Format: Article
Language:English
Published: Taylor & Francis Group 2020-11-01
Series:Animal Cells and Systems
Subjects:
bmp
fgf
erk
jnk
Online Access:http://dx.doi.org/10.1080/19768354.2020.1847732