Pomalidomide Ameliorates H2O2-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and Anti-Apoptosis Effects

Pomalidomide Ameliorates H2O2-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and Anti-Apoptosis Effects

Due to its high oxygen demand and abundance of peroxidation-susceptible lipid cells, the brain is particularly vulnerable to oxidative stress. Induced by a redox state imbalance involving either excessive generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system, oxidative...

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Bibliographic Details
Main Authors: Yan-Rou Tsai, Cheng-Fu Chang, Jing-Huei Lai, John Chung-Che Wu, Yen-Hua Chen, Shuo-Jhen Kang, Barry J. Hoffer, David Tweedie, Weiming Luo, Nigel H. Greig, Yung-Hsiao Chiang, Kai-Yun Chen
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
pomalidomide
neuroprotection
oxidative stress
ischemia
stroke
neurodegeneration
Online Access:http://www.mdpi.com/1422-0067/19/10/3252

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http://www.mdpi.com/1422-0067/19/10/3252

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