Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation

Expression of constitutively activated Akt in the mammary glands of transgenic mice results in a delay in post-lactational involution. We now report precocious lipid accumulation in the alveolar epithelium of mouse mammary tumor virus-myr-Akt transgenic mice accompanied by a lactation defect that re...

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Bibliographic Details
Main Authors: Kathryn L. Schwertfeger, James L. McManaman, Carol A. Palmer, Margaret C. Neville, Steven M. Anderson
Format: Article
Language:English
Published: Elsevier 2003-06-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520311111