Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation
Expression of constitutively activated Akt in the mammary glands of transgenic mice results in a delay in post-lactational involution. We now report precocious lipid accumulation in the alveolar epithelium of mouse mammary tumor virus-myr-Akt transgenic mice accompanied by a lactation defect that re...
Main Authors: | Kathryn L. Schwertfeger, James L. McManaman, Carol A. Palmer, Margaret C. Neville, Steven M. Anderson |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-06-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520311111 |
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