The osteopontin level in liver, adipose tissue and serum is correlated with fibrosis in patients with alcoholic liver disease.

The osteopontin level in liver, adipose tissue and serum is correlated with fibrosis in patients with alcoholic liver disease.

BACKGROUND: Osteopontin (OPN) plays an important role in the progression of chronic liver diseases. We aimed to quantify the liver, adipose tissue and serum levels of OPN in heavy alcohol drinkers and to compare them with the histological severity of hepatic inflammation and fibrosis. METHODOLOGY/PR...

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Bibliographic Details
Main Authors: Stéphanie Patouraux, Stéphanie Bonnafous, Cosmin S Voican, Rodolphe Anty, Marie-Christine Saint-Paul, Maria-Alessandra Rosenthal-Allieri, Hélène Agostini, Micheline Njike, Nadége Barri-Ova, Sylvie Naveau, Yannick Le Marchand-Brustel, Pascal Veillon, Paul Calès, Gabriel Perlemuter, Albert Tran, Philippe Gual
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3329460?pdf=render

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http://europepmc.org/articles/PMC3329460?pdf=render

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