Six Serum miRNAs Fail to Validate as Myotonic Dystrophy Type 1 Biomarkers.

Six Serum miRNAs Fail to Validate as Myotonic Dystrophy Type 1 Biomarkers.

Myotonic dystrophy type 1 (DM1) is an autosomal dominant genetic disease caused by expansion of a CTG microsatellite in the 3' untranslated region of the DMPK gene. Despite characteristic muscular, cardiac, and neuropsychological symptoms, CTG trinucleotide repeats are unstable both in the soma...

Full description

Bibliographic Details
Main Authors: Juan M Fernandez-Costa, Beatriz Llamusi, Ariadna Bargiela, Miren Zulaica, M Carmen Alvarez-Abril, Manuel Perez-Alonso, Adolfo Lopez de Munain, Arturo Lopez-Castel, Ruben Artero
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4769077?pdf=render

Internet

http://europepmc.org/articles/PMC4769077?pdf=render

Similar Items