A Randomized Trial of Pharmacogenetic Warfarin Dosing in Naïve Patients with Non-Valvular Atrial Fibrillation.

UNLABELLED:Genotype-guided warfarin dosing have been proposed to improve patient’s management. This study is aimed to determine whether a CYP2C9- VKORC1- CYP4F2-based pharmacogenetic algorithm is superior to a standard, clinically adopted, pharmacodynamic method. Two-hundred naïve patients with non-...

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Main Authors: Vittorio Pengo, Carlo-Federico Zambon, Paola Fogar, Andrea Padoan, Giovanni Nante, Michela Pelloso, Stefania Moz, Anna Chiara Frigo, Francesca Groppa, Dania Bozzato, Enrico Tiso, Elisa Gnatta, Gentian Denas, Seena Padayattil Jose, Roberto Padrini, Daniela Basso, Mario Plebani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4692529?pdf=render