Antipsychotic Drugs Inhibit Platelet Aggregation via P2Y1 and P2Y12 Receptors

Antipsychotic drugs (APDs) used to treat clinical psychotic syndromes cause a variety of blood dyscrasias. APDs suppress the aggregation of platelets; however, the underlying mechanism remains unknown. We first analyzed platelet aggregation and clot formation in platelets treated with APDs, risperid...

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Bibliographic Details
Main Authors: Chang-Chieh Wu, Fu-Ming Tsai, Mao-Liang Chen, Semon Wu, Ming-Cheng Lee, Tzung-Chieh Tsai, Lu-Kai Wang, Chun-Hua Wang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2016/2532371