A urine extracellular vesicle circRNA classifier for detection of high-grade prostate cancer in patients with prostate-specific antigen 2–10 ng/mL at initial biopsy

A urine extracellular vesicle circRNA classifier for detection of high-grade prostate cancer in patients with prostate-specific antigen 2–10 ng/mL at initial biopsy

Abstract The aim of this study was to identify a urine extracellular vesicle circular RNA (circRNA) classifier that could detect high-grade prostate cancer (PCa) of Grade Group (GG) 2 or greater. For this purpose, we used RNA sequencing to identify candidate circRNAs from urinary extracellular vesic...

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Bibliographic Details
Main Authors: Ya-Di He, Wen Tao, Tao He, Bang-Yu Wang, Xiu-Mei Tang, Liang-Ming Zhang, Zhen-Quan Wu, Wei-Ming Deng, Ling-Xiao Zhang, Chun-Kui Shao, Jing Zhou, Li-Min Rong, Xin Gao, Liao-Yuan Li
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Cancer
Subjects:
Prostate cancer
Circular RNA (circRNA)
Diagnosis
Urine
Extracellular vesicle
Online Access:https://doi.org/10.1186/s12943-021-01388-6

Internet

https://doi.org/10.1186/s12943-021-01388-6

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