Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection

Immune cell phenotypes associated with disease severity and long-term neutralizing antibody titers after natural dengue virus infection

Summary: Prior immunological exposure to dengue virus can be both protective and disease-enhancing during subsequent infections with different dengue virus serotypes. We provide here a systematic, longitudinal analysis of B cell, T cell, and antibody responses in the same patients. Antibody response...

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Bibliographic Details
Main Authors: Angeline Rouers, Melissa Hui Yen Chng, Bernett Lee, Menaka P. Rajapakse, Kaval Kaur, Ying Xiu Toh, Durgalakshmi Sathiakumar, Thomas Loy, Tun-Linn Thein, Vanessa W.X. Lim, Amit Singhal, Tsin Wen Yeo, Yee-Sin Leo, Kalpit A. Vora, Danilo Casimiro, Bing Lim, Lisa Tucker-Kellogg, Laura Rivino, Evan W. Newell, Katja Fink
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Cell Reports Medicine
Subjects:
dengue
longitudinal study
disease severity
immune cell phenotype
CyTOF
neutralizing antibodies
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121001063

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http://www.sciencedirect.com/science/article/pii/S2666379121001063

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