Pre-Activation of Toll-Like Receptor 2 Enhances CD8+ T-Cell Responses and Accelerates Hepatitis B Virus Clearance in the Mouse Models

Pre-Activation of Toll-Like Receptor 2 Enhances CD8+ T-Cell Responses and Accelerates Hepatitis B Virus Clearance in the Mouse Models

Toll-like receptors (TLRs) play a crucial role in activation of innate immunity, which is essential for inducing effective adaptive immune responses. Our previous studies have shown that toll-like receptor 2 (TLR2) is required to induce effective virus-specific T-cell responses against hepatitis B v...

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Bibliographic Details
Main Authors: Yong Lin, Xuan Huang, Jun Wu, Jia Liu, Mingfa Chen, Zhiyong Ma, Ejuan Zhang, Yan Liu, Shunmei Huang, Qian Li, Xiaoyong Zhang, Jinlin Hou, Dongliang Yang, Mengji Lu, Yang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
toll-like receptor 2
hepatitis B virus
mouse model
proinflammatory cytokines
T-cell immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01495/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.01495/full

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