Advantages of Utilizing Population Balance Modeling of Crystallization Processes for Particle Size Distribution Prediction of an Active Pharmaceutical Ingredient

Active pharmaceutical ingredient (API) particle size distribution is important for both downstream processing operations and in vivo performance. Crystallization process parameters and reactor configuration are important in controlling API particle size distribution (PSD). Given the large number of...

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Bibliographic Details
Main Authors: Tamar Rosenbaum, Li Tan, Joshua Engstrom
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Processes
Subjects:
Online Access:https://www.mdpi.com/2227-9717/7/6/355