Effect of Maternal Obesity in Mice on IL-6 Levels and Placental Endothelial Cell Homeostasis

Effect of Maternal Obesity in Mice on IL-6 Levels and Placental Endothelial Cell Homeostasis

Obesity during pregnancy is a known health risk for mother and child. Since obesity is associated with increased inflammatory markers, our objectives were to determine interleukin-6 (IL-6) levels in obese mice and to examine the effect of IL-6 on placental endothelial cells. Placentas, blood, and ad...

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Bibliographic Details
Main Authors: Tobias Kretschmer, Merle Schulze-Edinghausen, Eva-Maria Turnwald, Ruth Janoschek, Inga Bae-Gartz, Peter Zentis, Marion Handwerk, Maria Wohlfarth, Astrid Schauss, Eva Hucklenbruch-Rother, Jörg Dötsch, Sarah Appel
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nutrients
Subjects:
pregnancy
inflammation
placental vascular insufficiency
placental dysfunction
epigonadal white adipose tissue
human placental vein endothelial cells
il-6-induced senescence
pregnancy outcomes
Online Access:https://www.mdpi.com/2072-6643/12/2/296

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https://www.mdpi.com/2072-6643/12/2/296

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