Impaired decision making and loss of inhibitory-control in a rat model of Huntington disease

Impaired decision making and loss of inhibitory-control in a rat model of Huntington disease

Cognitive deficits associated with Huntington disease (HD) are generally dominated by executive function disorders often associated with disinhibition and impulsivity/compulsivity. Few studies have directly examined symptoms and consequences of behavioral disinhibition in HD and its relation with de...

Full description

Bibliographic Details
Main Authors: Nicole El Massioui, Charlotte Lamirault, Sara Yagüe, Najia Adjeroud, Daniel Garces, Alexis Maillard, Lucille Tallot, Libo Yu-Taeger, Olaf Riess, Philippe Allain, Huu Phuc Nguyen, Stephan Von Hörsten, Valérie Doyère
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Huntington Disease
decision-making
impulsivity
delay discounting
gambling task
DrL
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00204/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2016.00204/full

Similar Items