The chromodomain helicase CHD4 regulates ERBB2 signaling pathway and autophagy in ERBB2+ breast cancer cells
The chromodomain helicase DNA-binding 4 (CHD4), a member of the nucleosome remodeling and deacetylases (NuRD) complex, has been identified as an oncogene that modulates proliferation and migration of breast cancers (BC). ERBB2 is an oncogenic driver in 20–30% of BC in which its overexpression leads...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2019-04-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/8/4/bio038323 |